Immunological Features of Juvenile Offenders

We assume that complex mental changes caused by penal stress are often accompanied by a decline in the immune response. Evaluation immunophysiological shifts in people adolescence that are conditions of detention are the target of this study. A total of 57 adolescents, 47 of them students of educational colonies of Russia's largest cities, and 10 students of secondary and higher educational institutions of the city are surveyed. They examined the immune status by standardized methods. Phagocytic index and phagocytic number of polymorphonuclear leucocytes of the adolescents containing in educational colony, had considerably below norm. At the analysis of absolute quantity T-helpers and T-suppressors is revealed CD4, or isolated activation of CD8. It is drawn a conclusion, that adaptable reaction to conditions of a punishment cell is accompanied by phase changes of the immune status which expressiveness has specific features. In conditions of holding in custody strengthening immunosuppressor and cytotoxic effect that is shown by activation T-effectors and NK-cells becomes leader and a parallel decrease in the proportion of T-helper cells. It is formed Th2-helper type of immune response, characterized by the suppression of cellular responses and prerequisites for the prevalence of humoral response.